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Apo-Warfarin (CA), Coumadin, Gen-Warfarin (CA), Jantoven, Marevan (UK), Novo-Warfarin (CA), Taro-Warfarin (CA)Pharmacologic class: Coumarin derivative Therapeutic class: Anticoagulant Pregnancy risk category X• Drug may cause major or fatal bleeding. daily.• Hypersensitivity to drug• Uncontrolled bleeding• Open wounds• Severe hepatic disease• Hemorrhagic or bleeding tendency• Cerebrovascular hemorrhage• Cerebral aneurysm or dissecting aorta• Blood dyscrasias• Pericarditis or pericardial effusion• Bacterial endocarditis• Malnant hypertension• Recent brain, eye, or spinal cord injury or surgery• Lumbar puncture and other procedures that may cause uncontrollable bleeding• Major regional or lumbar block anesthesia• Threatened abortion, eclampsia, preeclampsia• Unsupervised senile, alcoholic, or psychotic patients• Pregnancy, females of childbearing potential Use cautiously in:• cancer, heparin-induced thrombocytopenia, moderate to severe renal impairment, moderate to severe hypertension, infectious GI disease, known or suspected deficiency in protein C-mediated anticoagulant response, polycythemia vera, vasculitis, severe diabetes mellitus• indwelling catheter use• history of poor compliance• elderly or debilitated patients• breastfeeding patients• children younger than age 18 (safety and efficacy not established). If major bleeding occurs, fresh frozen plasma may be given.• When converting to warfarin from heparin, give both drugs concomitantly for 4 to 5 days until therapeutic effect of warfarin occurs.

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Prednisone and cumadin:

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